Benadryl challenge

The Benadryl challenge is an internet challenge that emerged in 2020, revolving around the deliberate consumption, excessive use and overdose of the antihistamine medicine diphenhydramine, which acts as a deliriant in high doses. The challenge, which spread via the social media platform TikTok, instructs participants to film themselves consuming large doses of Benadryl and documenting the effect of tripping or hallucinating.