Saginaw is a city in the U.S. state of Michigan and the seat of Saginaw County. The city of Saginaw and Saginaw County are both in the area known as Mid-Michigan. Saginaw is adjacent to Saginaw Charter Township and considered part of Greater Tri-Cities region of Central Michigan. The Saginaw County MSA had a population of 190,124 in 2020. The city is also the largest municipality in the Saginaw, Midland, and Bay City Metropolitan Area, with a combined population of 377,474 in the combined statistical area in 2020. The city proper had a population of 44,202 at the 2020 census.